Quality of clinical studies present in the package inserts of coagulation factors used in the treatment of hemophilia.
Yasmin Gonçalves AraújoJoão Pedro Vasconcelos PaolinelliJanaina Souza Dias PichitelliDanyelle Romana Alves RiosNayara Ragi BaldoniAndré de Oliveira BaldoniPublished in: Einstein (Sao Paulo, Brazil) (2022)
The biases present are significant and may have influenced the overestimation of the effects of the outcomes of each of the studies.