High incidence of asymptomatic phase I IgG seroconversion after acute Q fever episode: implications for chronic Q fever diagnosis.
Miguel Rodríguez-FernándezReinaldo Espíndola GómezMarta Trigo-RodríguezCarmen CastroPedro Martínez Pérez-CrespoRocío HerreroEva M LeónSamuel BernalJuan E CorzoNicolás MerchantePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
A significant proportion of acute Q fever patients develops classic serologic criteria for chronic Q fever diagnosis in the absence of additional data of chronic Q fever. Consequently, phase I IgG cutoff titer > 1:800 should not be used as a criterion to consider such a diagnosis. The incidence of persistent focalized infection forms after acute Q fever is extremely low and does not justify the use of prophylaxis strategies.