Login / Signup

Combination of two monoclonal ACPAs induced tenosynovitis, pain and bone loss in mice in a Peptidyl Arginine Deiminase-4 dependent manner.

Akilan KrishnamurthyAlexandra CirciumaruJitong SunYogan KistenPeter DambergKoji SakurabaKatalin SandorPatrik JarvollTunhe ZhouVivianne MalmströmCamilla I SvenssonAase HensvoldAnca I CatrinaLars KlareskogBence Rethi
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
Monoclonal ACPAs can induce tenosynovitis in addition to pain and bone loss via mechanisms dependent on PAD4-mediated citrullination. This article is protected by copyright. All rights reserved.
Keyphrases
  • bone loss
  • chronic pain
  • pain management
  • neuropathic pain
  • nitric oxide
  • high glucose
  • diabetic rats
  • spinal cord injury
  • type diabetes
  • drug induced
  • spinal cord
  • metabolic syndrome
  • insulin resistance