Epigenetic signatures in gastric cancer: current knowledge and future perspectives.
Fatma SogutluMert PekerbasÇigir Biray AvciPublished in: Expert review of molecular diagnostics (2022)
Epigenetic alterations take place before most genetic aberrations observed in GC and may have an initiating role in the pathogenesis of GC. They can be used as biomarkers in risk calculation, early diagnosis, and evaluation of prognosis of GC, as well as treatment targets.