TMEM106B aggregation in neurodegenerative diseases: linking genetics to function.
Hai-Shan JiaoPeng YuanJin-Tai YuPublished in: Molecular neurodegeneration (2023)
TMEM106B mutations could lead to lysosome dysfunction by promoting the aggregation of TMEM106B and reducing these aggregations may restore lysosomal function, providing a potential therapeutic target for various neurodegenerative diseases.
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