Fibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by 68 Ga-FAPI-PET imaging.
Esther StratingEmma WassenaarMathijs VerhagenPaulien RauwerdinkSusanne van SchelvenIgnace de HinghInne Borel RinkesDjamila BoermaArjen WitkampMiangela LacleRiccardo FoddeRichard VolckmannJan KosterKris StedingkFrederik GieselRemmert de RoosAlex PootGuus BolMarnix G E H LamSjoerd G EliasOnno W KranenburgPublished in: British journal of cancer (2022)
FAP expression identifies CMS4 CRC. FAPI-PET may have value in the comprehensive detection of CMS4 tumours in CRC. This is especially relevant in patients with PM, for whom effective imaging tools are currently lacking.
Keyphrases
- pet imaging
- pet ct
- genome wide
- loop mediated isothermal amplification
- positron emission tomography
- real time pcr
- high resolution
- label free
- computed tomography
- air pollution
- particulate matter
- binding protein
- dna methylation
- heavy metals
- clinical practice
- long non coding rna
- photodynamic therapy
- wound healing
- fluorescence imaging