Rates of symptomatology are lower in recurrent sinonasal malignancy than in other recurrent cancers of the head and neck: a multi-institutional study.
Alan D WorkmanNathalia VelasquezNayel I KhanNicole A BorchardEdward Cheng-Lung KuanJames N PalmerEric W WangZara M PatelNithin D AdappaPublished in: International forum of allergy & rhinology (2019)
Patients with sinonasal malignancy have a much lower rate of symptomatology during tumor recurrence than that observed in head and neck cancer overall. Furthermore, time to recurrence is substantially longer, as a majority of head and neck cancer recurrences occur in the first 12 months after treatment. These differences highlight the need for more tailored surveillance paradigms in asymptomatic patients with a history of a definitively treated sinonasal neoplasm.