Altered Repertoire Diversity and Disease-Associated Clonal Expansions Revealed by T Cell Receptor Immunosequencing in Ankylosing Spondylitis Patients.

Aimee L HansonHendrik J NelLinda BradburyJulie PhippsRanjeny ThomasKim-Anh Lê CaoTony J KennaMatthew A Brown

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2020)

The dynamics of peripheral T cell responses in AS patients are altered, suggesting that differential antigen exposure and disrupted adaptive immunity are underlying features of the disease.

Keyphrases

health insurance
end stage renal disease
ankylosing spondylitis
ejection fraction
newly diagnosed
peritoneal dialysis
rheumatoid arthritis
high throughput sequencing