The genetic deletion of the Dual Specificity Phosphatase 3 (DUSP3) attenuates kidney damage and inflammation following ischaemia/reperfusion injury in mouse.
Badr KhbouzPascal RowartLaurence PomaEileen DahlkeMartina BottnerMatthew StokesGéraldine BolenSouad RahmouniFranziska TheiligFrançois JouretPublished in: Acta physiologica (Oxford, England) (2021)
Genetic inactivation of Dusp3 is associated with kidney conditioning against I/R, possibly due to attenuated inflammation and improved perfusion.