Benefits of Adjuvant Mitotane after Resection of Adrenocortical Carcinoma: A Systematic Review and Meta-Analysis.

Yongquan TangZhihong LiuZijun ZouJiayu LiangYiping Lu Yuchun Zhu

Published in: BioMed research international (2018)

After comprehensive review, current evidence suggests that adjuvant mitotane significantly decreases the recurrence rate and mortality after resection of ACC in patients without distant metastasis, but these findings need further demonstration from prospective controlled trials.

Keyphrases

end stage renal disease
early stage
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
lymph node
prognostic factors