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Nlrp3 inflammasome drives regulatory T cell depletion to accelerate periapical bone erosion.

Konghuai WangJiayi LiuJunli YueLu ZhouHanqing MaoJiaqi LiZhijun SunChen ZhiLu Zhang
Published in: International endodontic journal (2024)
Together, our data identify that the Nlrp3 inflammasome modulates the Treg cell stability and osteoclastogenesis in the periapical inflammatory microenvironment, thus determining the progression of bone erosion.
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