ImmunoPET imaging of multiple myeloma with [68Ga]Ga-NOTA-Nb1053.

Cheng WangYumei ChenYun Nan HouQiufang LiuDi ZhangHaitao ZhaoYou ZhangShuxian AnLianghua LiJian HouGang HuangJianjun LiuYong Juan ZhaoWeijun Wei

Published in: European journal of nuclear medicine and molecular imaging (2021)

This work successfully developed a novel CD38-targeted immunoPET imaging approach that enabled precise visualization of CD38 and diagnosis of MMs. Upon clinical translation, [68Ga]Ga-NOTA-Nb1053 immunoPET may serve as a valuable CD38-targeted molecular imaging toolbox, facilitating early diagnosis of MM and precise assessment of the therapeutic responses.

Keyphrases

pet ct
high resolution
multiple myeloma
cancer therapy
nk cells
mass spectrometry
fluorescence imaging
photodynamic therapy