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Association between Previous Pelvic Radiation and All-Cause and Cause-Specific Failure of Replacement Artificial Urinary Sphincters.

Mitchell M HuangPhillip HuffmanHasan DaniPedro G KnijnikArthur F da SilvaArthur L BurnettJacek L MostwinEdward J WrightAndrew J Cohen
Published in: The Journal of urology (2022)
Among men with a replacement AUS, a history of pelvic radiation was associated with shorter time to device failure of any cause. Radiation was also specifically associated with a sevenfold increase in the risk of erosion or infection of replacement AUS, but not with urethral atrophy or mechanical failure. Patients with a replacement AUS should be appropriately counseled on how radiation history may impact outcomes of future revisions.
Keyphrases
  • radiation induced
  • rectal cancer
  • radiation therapy
  • adipose tissue
  • insulin resistance