Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope.

Manisha ShrivastavElias GounarisMohammad W KhanJeffrey KoStacy H RyuMatthew BogyoAndrew LarsonTerrence A BarretDavid J Bentrem

Published in: PloS one (2018)

The dual laser NIRF endoscope is a powerful tool to validate probes. The probes that react catalytically with the active center of cathepsins are more efficient than the ones that react stoichiometrically in detecting small lesions.

Keyphrases

single molecule
small molecule
living cells
fluorescence imaging
fluorescent probe
nucleic acid
high speed
photodynamic therapy