Serum soluble sialic acid-binding immunoglobulin-like lectin-7 concentration as an indicator of liver macrophage activation and advanced fibrosis in patients with non-alcoholic fatty liver disease.

Yuzuru Sakamoto Sachiyo YoshioHiroyoshi DoiHironari KawaiTomonari ShimagakiTaizo MoriMichitaka MatsudaYoshihiko AokiYosuke OsawaYuji YoshidaTaeang AraiNorio ItokawaTakanori ItoYuya SekoKanji YamaguchiYoshihito ItohYoshihiro MiseAkio SaiuraAkinobu TaketomiTatsuya Kanto

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2019)

Elevated serum sSiglec-7 could serve as an independent marker with high specificity for advanced liver fibrosis in patients with NAFLD.

Keyphrases

liver fibrosis
adipose tissue
binding protein
dna binding
transcription factor