A Bivalent Omicron-Containing Booster Vaccine against Covid-19.
Spyros ChalkiasCharles HarperKeith VrbickyStephen R WalshBrandon EssinkAdam BroszNichole McGheeJoanne E TomassiniXing ChenYing ChangAndrea SutherlandDavid C MontefioriBethany GirardDarin K EdwardsJing FengHonghong ZhouLindsey R BadenJacqueline M MillerRituparna DasPublished in: The New England journal of medicine (2022)
The bivalent omicron-containing vaccine mRNA-1273.214 elicited neutralizing antibody responses against omicron that were superior to those with mRNA-1273, without evident safety concerns. (Funded by Moderna; ClinicalTrials.gov number, NCT04927065.).