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Advancing a rapid, high throughput screening platform for optimization of lentivirus production.

Sneha GopalAdam E OsborneLindsay HockJill ZemianekKun FangGretchen GeeRonit GhoshDavid McNallySteven M CramerJonathan S Dordick
Published in: Biotechnology journal (2021)
The ability to test a large number of conditions simultaneously with minimal reagent use allows for the rapid optimization of LVV production in HEK293 suspension cells. Therefore, such a system may serve as a valuable tool in early stage process development and can be used as a screening tool to improve LVV concentrations for both batch and perfusion based systems.
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