Interaction between apolipoprotein E genotypes, excessive daytime sleepiness, and cognitive function in obstructive sleep apnea patients.

Fernanda Maurer Balthazar Walter André Dos Santos Moraes James Richard Hunter Gilmar Fernandes do Prado Luciane Bizari Coin de Carvalho

Published in: Arquivos de neuro-psiquiatria (2022)

Excessive daytime sleepiness and the ApoEε3/ε4 genotype are associated with worse cognitive performance in OSA patients. The combination of EDS and ε4 allele potentiates cognitive impairment.

Keyphrases

obstructive sleep apnea
end stage renal disease
positive airway pressure
ejection fraction
newly diagnosed
cognitive impairment
chronic kidney disease
sleep quality
prognostic factors
type diabetes
cognitive decline
high fat diet
weight gain
physical activity
patient reported outcomes
adipose tissue
weight loss