Peripheral Nerve Blockade with Combined Standard and Liposomal Bupivacaine in Major Lower-Extremity Amputation.
Catalina I DumitrascuNafisseh S WarnerThomas M StewartAdam W AmundsonDanette L BrunsAndrew C HansonPhillip J SchulteMark M SmithMichael J BrownAdam D NiesenCarlos B MantillaMatthew A WarnerPublished in: Pain practice : the official journal of World Institute of Pain (2020)
Peripheral nerve blockade is associated with reduced opioid requirements after lower-extremity amputation compared with general anesthesia alone. However, the incorporation of liposomal bupivacaine is not significantly different to blockade employing only standard bupivacaine.