Functional lower airways genomic profiling of the microbiome to capture active microbial metabolism.

Imran SulaimanBenjamin G WuYonghua LiJun-Chieh TsayMaya SauthoffAdrienne S ScottKun JiSergei B KoralovMichael WeidenJose C ClementeDrew R JonesYvonne J HuangKathleen A StringerLingdi ZhangAdam GeberStephanie BanakisLaura TiptonElodie GhedinLeopoldo N Segal

Published in: The European respiratory journal (2021)

Functional characterisation of the lower airway microbiota through metatranscriptome data identifies metabolically active organisms capable of producing metabolites with immunomodulatory capacity, such as SCFAs.

Keyphrases

ms ms
microbial community
big data
electronic health record
single cell
genome wide
copy number
gene expression
multidrug resistant