[Application of the method of liquid chromato-mass spectrometry for determination of bisoprolol and atorvastatin.]
N E DukhovskayaT P VavilovaS Yu GorbachevaP V GremyakovaI G OstrovskayaPublished in: Klinicheskaia laboratornaia diagnostika (2019)
A technique has been developed for the quantitative determination of bisoprolol and atorvastatin in mixed saliva on a LCMS-8040 triple quadrupole liquid chromatographic mass spectrometer with ionization, separation and detection of samples, which allows determining the concentration in mixed saliva of bisoprolol with an accuracy of 93.7 to 98, 5% and atorvastatin from 95.6 to 98.3%.
Keyphrases
- liquid chromatography
- mass spectrometry
- solid phase extraction
- gas chromatography
- high resolution
- tandem mass spectrometry
- high performance liquid chromatography
- simultaneous determination
- molecularly imprinted
- ionic liquid
- capillary electrophoresis
- loop mediated isothermal amplification
- label free
- sensitive detection
- quantum dots