Impact of HIV Infection on COVID-19 Outcomes Among Hospitalized Adults in the U.S.
Matthew S DurstenfeldKaiwen SunYifei MaFatima RodriguezEric A SecemskyRushi V ParikhPriscilla Y HsuePublished in: medRxiv : the preprint server for health sciences (2021)
We studied 21,528 patients hospitalized with COVID-19 at 107 hospitals in AHA's COVID-19 registry to examine the association between HIV and COVID-19 outcomes. More patients with HIV were younger, male, non-Hispanic Black, on Medicaid and current smokers. HIV was not associated with worse COVID-19 in-hospital mortality (Risk ratio 1.06, 95%CI 0.79-1.43; p=0.71) even after adjustment (aOR 1.15; 95%CI 0.78-1.70; p=0.48). HIV was also not associated with MACE (aOR 0.99, 95%CI 0.69-1.44, p=0.91) or severity of illness (aOR 0.96, 95%CI 0.62-1.50, p=0.86. Our findings do not support that HIV is a major risk factor for adverse COVID-19 outcomes.
Keyphrases
- coronavirus disease
- antiretroviral therapy
- sars cov
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- healthcare
- respiratory syndrome coronavirus
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- south africa
- ejection fraction
- metabolic syndrome
- smoking cessation
- patient reported outcomes
- adipose tissue
- adverse drug
- skeletal muscle
- electronic health record