Plasma exosomes stimulate breast cancer metastasis through surface interactions and activation of FAK signaling.

Tatiana ShtamStanislav NaryzhnyRoman SamsonovDavid KarasikIgor MizgirevArtur KopylovElena PetrenkoYana ZabrodskayaRoman KamyshinskyDaniil NikitinMaxim SorokinAnton BuzdinHava Gil-HennAnastasia Malek

Published in: Breast cancer research and treatment (2018)

Plasma exosomes have a potency to stimulate the metastasis-promoting properties of BC cells. This pro-metastatic property of normal plasma exosomes may have impact on the course of the disease and on its prognosis.

Keyphrases

mesenchymal stem cells
stem cells
induced apoptosis
squamous cell carcinoma
small cell lung cancer