Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia.
Rashmi DasAbhishek Ankur BalmikSubashchandrabose ChinnathambiPublished in: Journal of neuroinflammation (2020)
The peri-membrane polymerization of actin filament and co-localization of Iba1 relate to the microglial movements for phagocytosis. Here, these findings suggest that microglia modified actin cytoskeleton for phagocytosis and rapid clearance of Tau oligomers in Alzheimer's disease condition.