Causes of death in patients with locally advanced head and neck cancer treated with radiotherapy and systemic therapy.
I ZapataM AlvarezR HidalgoB PajaresM J Garcia-AnayaM D ToledoJ M TrigoY Lupiañez-PerezJ A MedinaJaime Gómez-MillánPublished in: BMC cancer (2019)
This study demonstrated a high incidence of competing mortality in older patients with comorbidities. Non-cancer deaths should be considered when selecting patients for combination therapies and in the study design ofclinical trials.
Keyphrases
- locally advanced
- newly diagnosed
- end stage renal disease
- squamous cell carcinoma
- ejection fraction
- rectal cancer
- risk factors
- chronic kidney disease
- neoadjuvant chemotherapy
- early stage
- papillary thyroid
- physical activity
- cardiovascular events
- cardiovascular disease
- clinical trial
- radiation induced
- stem cells
- patient reported outcomes
- squamous cell
- community dwelling
- coronary artery disease
- smoking cessation
- lymph node metastasis
- childhood cancer
- replacement therapy
- open label
- drug induced
- double blind