Genomic Landscape of Patients with Germline RUNX1 Variants and Familial Platelet Disorder with Myeloid Malignancy.

Kai Yu Natalie T DeuitchMatthew MerguerianLea CunninghamJoie DavisErica BrescianiJamie DiemerElizabeth AndrewsAlice YoungFrank DonovanRaman SoodKathleen CraftShawn ChongSettara ChandrasekharappaMay Christine V MalicdanPaul P Liu

Published in: bioRxiv : the preprint server for biology (2023)

mutations. Rising clonal hematopoiesis related secondary mutations that may lead to myeloid malignancies.

Keyphrases

copy number
dendritic cells
bone marrow
acute myeloid leukemia
dna repair
single cell
immune response
gene expression
oxidative stress
dna methylation
genome wide
dna damage