Polygenic Risk of Prediabetes, Undiagnosed Diabetes, and Incident Type 2 Diabetes Stratified by Diabetes Risk Factors.

Xiaonan LiuJennifer A CollisterLei CliftonDavid J HunterThomas J Littlejohns

Published in: Journal of the Endocrine Society (2023)

Genetic risk of type 2 diabetes remains strongly associated with risk of prediabetes, undiagnosed diabetes, and future type 2 diabetes within categories of nongenetic risk factors. This could have important implications for identifying individuals at risk of type 2 diabetes for prevention and early diagnosis programs.

Keyphrases

type diabetes
glycemic control
risk factors
cardiovascular disease
insulin resistance
public health
genome wide
current status
adipose tissue
dna methylation