[Pre-rehabilitation of oncological patients before extensive abdominal and thoracic surgery: a literature review].
E A MelnikovaE Yu StarkovaA V SemenkovV Yu LitauD A TulskihPublished in: Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury (2024)
Surgery is one of the leading treatment methods of patients with primary or recurrent malignant neoplasms in the thoracic or abdominal cavity. Extensive abdominal interventions are accompanied by such adverse outcomes as blood loss, hypoxia, inflammation, blood clotting abnormality, emotional and cognitive disorders, that increases the incidence of serious complications and worsens the treatment outcome and life quality in weakened oncological patients. Multimodal pre-rehabilitation before surgery can significantly decrease the incidence and severity of postoperative complications. The rehabilitation complex includes exercise therapy, nutritional and psychological support, smoking cessation and pharmacotherapy. Currently, there are a number of questions facing rehabilitation specialists and oncologists, that are related to the determination of pre-rehabilitation optimal timing and process duration, the choice of specific physical exercises, determining the load intensity. This review presents a current view on understanding of surgical stress in extensive abdominal interventions, its effect on the oncological process course, summarizes the experience of last years in choosing pre-rehabilitation program taking into account pathogenetic mechanisms of surgical stress and individual patient's characteristics. Special attention is paid to the comparison of physical exercises' various types, their action mechanisms at different stages of pathological process, the issues of load dosing during pre-rehabilitation activities.
Keyphrases
- smoking cessation
- end stage renal disease
- physical activity
- ejection fraction
- newly diagnosed
- chronic kidney disease
- minimally invasive
- prognostic factors
- peritoneal dialysis
- case report
- risk factors
- mental health
- high intensity
- oxidative stress
- prostate cancer
- coronary artery bypass
- radical prostatectomy
- stem cells
- resistance training
- patient reported outcomes
- high resolution
- bone marrow
- decision making
- pain management
- combination therapy
- cell therapy
- sleep quality
- clinical evaluation