Glucocorticoid-induced adrenal insufficiency after therapy with intravenous methylprednisolone in patients with moderate-to-severe and active Graves' orbitopathy: assessment with a low-dose corticotropin test.
Katarzyna PelewiczP MiśkiewiczPublished in: Journal of endocrinological investigation (2024)
For the first time, our research shows that administering IVMP in 12 weekly pulses can result in GC-induced AI. We suggest that patients should undergo careful evaluation for GC-induced AI, including LDT, after therapy with IVMP according to EUGOGO guidelines. Screening for altered adrenal reserve could prevent life-threatening complications, particularly during acute stress situations.
Keyphrases
- low dose
- drug induced
- high glucose
- diabetic rats
- high dose
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- ejection fraction
- prognostic factors
- early onset
- machine learning
- intensive care unit
- aortic dissection
- stress induced
- acute respiratory distress syndrome
- deep learning
- heat stress
- smoking cessation