Notch activation promotes bone metastasis via SPARC inhibition in adenoid cystic carcinoma.

Ye ZhangXiaoxiao LiuLijing ZhuZheng ZhouYajuan CuiChuan-Xiang ZhouTie-Jun Li

Published in: Oral diseases (2023)

Notch activation in AdCC contributes to bone metastasis through SPARC inhibition. The study results suggest that SPARC may represent a prognostic biomarker and potential therapeutic target.

Keyphrases

bone mineral density
cell proliferation
soft tissue
bone loss
bone regeneration
body composition