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Synthesis of benzo[ f ][1,2]thiazepine 1,1-dioxides based on the visible-light-mediated aza Paternò-Büchi reaction of benzo[ d ]isothiazole 1,1-dioxides with alkenes.

Yi-Lin WangPeng-Xiang LiuHuan-Huan ZhangPeng-Fei XuYong-Chun Luo
Published in: Chemical communications (Cambridge, England) (2023)
A new two-step, one-pot synthesis of benzo[ f ][1,2]thiazepine 1,1-dioxides was developed, which contains a visible-light mediated aza Paternò-Büchi reaction of benzo[ d ]isothiazole 1,1-dioxides with alkenes and a Lewis acid catalyzed ring-expansion of azetidine. In this work, the mechanism of the aza Paternò-Büchi reaction was also investigated.
Keyphrases
  • visible light
  • mass spectrometry
  • high resolution