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Migraine heritability and beyond: A scoping review of twin studies.

Isa Amalie Olofsson
Published in: Headache (2024)
The heritability of migraine was estimated with a classical twin design in twin cohorts from seven different countries, with remarkably similar results across studies. Future studies should include migraine subtypes and twin cohorts of non-North European ancestry to better reflect the global population. Beyond heritability estimations, the twin method is a valuable tool for understanding causality and describing differences within discordant twin pairs. Despite more than 80 years of twin studies in migraine research, the twin design has a large unused potential to advance our understanding of migraine.
Keyphrases
  • case control
  • emergency department
  • risk assessment
  • genome wide association study