STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice.

Weiman HeZhen ChengZijun HuoBo LinXuejie WangYijia SunShuang YuSiting CaoJunyu XueRengyun LiuWeiming LvYanbing Li Shubin Hong Hai-Peng Xiao

Published in: Endocrinology (2023)

Our study demonstrates the critical roles of STRA6 contributing to TC progression via the ILK/AKT/mTOR axis, which may provide a novel prognostic marker as well as a promising therapeutic target for aggressive TC.

Keyphrases

cell proliferation
signaling pathway
induced apoptosis
cell cycle arrest
high fat diet induced
endoplasmic reticulum stress
oxidative stress
cell death
adipose tissue