Sarcopenic Obesity Is a Risk Factor for Worse Oncological Long-Term Outcome in Locally Advanced Rectal Cancer Patients: A Retrospective Single-Center Cohort Study.
Peter TschannMarkus P WeiglPatrick ClemensPhilipp SzeverinskiChristian AttenbergerMatthias KowatschTarkan JägerKlaus EmmanuelThomas BrockIngmar KönigsrainerPublished in: Nutrients (2023)
Muscle waste, older age, and comorbidities were demonstrated as strong risk factors for increased overall morbidity. Sarcopenic obesity was associated with worse DFS and OS. This study underlines the role of nutrition and appropriate physical activity prior to therapy.
Keyphrases
- physical activity
- rectal cancer
- locally advanced
- insulin resistance
- metabolic syndrome
- weight loss
- type diabetes
- high fat diet induced
- weight gain
- skeletal muscle
- squamous cell carcinoma
- neoadjuvant chemotherapy
- body mass index
- heavy metals
- clinical trial
- radiation therapy
- stem cells
- prostate cancer
- phase ii study
- bone marrow
- radical prostatectomy
- robot assisted
- depressive symptoms
- community dwelling
- mesenchymal stem cells
- double blind
- anaerobic digestion