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MGMT Promoter Methylation Status in Initial and Recurrent Glioblastoma: Correlation Study with DWI and DSC PWI Features.

Hye Jeong ChoiSeung Hong ChoiSung-Hye YouRoh-Eul YooKoung Mi KangTae Jin YunJi Hoon KimChul-Ho SohnChul-Kee ParkHye-Kyung Park
Published in: AJNR. American journal of neuroradiology (2021)
MGMT promoter methylation status might change in recurrent glioblastoma after standard treatment. The normalized relative CBV values of the nonenhancing region at the first preoperative MR imaging were higher in the MGMT promoter methylation change group from methylation to unmethylation in recurrent glioblastoma.
Keyphrases
  • dna methylation
  • genome wide
  • gene expression
  • transcription factor
  • magnetic resonance
  • contrast enhanced
  • diffusion weighted imaging
  • combination therapy
  • diffusion weighted