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Development of an In Vitro Model for Inflammation Mediated Renal Toxicity Using 3D Renal Tubules and Co-Cultured Human Immune Cells.

Mi-Lang KyunTamina ParkHyewon JungInhye KimJi-In KwonSeo Yule JeongMyeongjin ChoiDaeui ParkYu Bin LeeKyoung-Sik Moon
Published in: Tissue engineering and regenerative medicine (2023)
The model demonstrated similar changes in kidney injury markers following polyI:C and LPS treatment, indicating its suitability for detecting immune-associated kidney damage resulting from infections and biopharmaceutical applications.
Keyphrases
  • oxidative stress
  • endothelial cells
  • inflammatory response