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Stratified reconstruction of ancestral Escherichia coli diversification.

José Maria Gonzalez-AlbaFernando BaqueroRafael CantónJuan Carlos Galán
Published in: BMC genomics (2019)
A staggered reconstruction of E. coli phylogeny is proposed, indicating evolution from three ancestral lineages to reach all main known phylogroups. New phylogroups were confirmed, suggesting an increasingly complex population structure of E. coli. However these new phylogroups represent < 1% of the global E. coli population. A few key evolutionary forces have driven the diversification of the two main E. coli lineages, metabolic flexibility in one of them and colonization-virulence in the other.
Keyphrases
  • escherichia coli
  • biofilm formation
  • klebsiella pneumoniae
  • staphylococcus aureus
  • genome wide
  • dna methylation
  • antimicrobial resistance
  • multidrug resistant