Novel vic-dioximes: synthesis, structure characterization, and antimicrobial activity evaluation.
Dumitru UrecheIon BulhacAlexandru CiocarlanDaniel RoshcaLucian LupascuPaulina BouroshPublished in: Turkish journal of chemistry (2021)
The vic-dioximes are compounds with various industrial uses and scientific applications. Many coordination compounds have been synthesized based on vic-dioximes. This study presents the synthesis and full characterization of two vic-dioximes based on dichloroglyoxime, p -aminobenzoic acid, and p -aminotoluene. Their structures were proved by IR, 1 H, 13 C and 15 N NMR spectral analysis, and single crystal X-ray diffraction. One of the reported vic-dioximes, bis (di- p -aminotoluene)glyoxime mono- p -aminotoluene trihydrate showed good to moderate antimicrobial activity against both nonpathogenic gram-positive and gram-negative bacteria ( Bacillus subtilis and Pseudomonas fluorescens ), phytopathogenic ( Xanthomonas campestris , Erwinia amylovora , E. carotovora ) and the fungi ( Candida utilis and Saccharomyces cerevisiae ) at MIC - 70-150 μg/mL.
Keyphrases
- saccharomyces cerevisiae
- bacillus subtilis
- high resolution
- biofilm formation
- magnetic resonance
- dual energy
- optical coherence tomography
- candida albicans
- wastewater treatment
- ionic liquid
- gram negative
- high intensity
- escherichia coli
- computed tomography
- pseudomonas aeruginosa
- risk assessment
- electron microscopy
- crystal structure