Palladium-Catalyzed ortho-C-H Arylation of Acetophenone Oxime Ethers with Aryl Pinacol Boronic Esters.

We report an efficient palladium-catalyzed ortho-C-H arylation of acetophenone oxime ethers with aryl pinacol boronic esters, leading to the synthesis of biaryl derivatives in good yields. Sequential process of iridium-catalyzed C-H borylation and palladium-catalyzed ortho-C-H arylation directed to access functionalized arenes.