The Role and Mechanism of Hyperoside against Depression-like Behavior in Mice via the NLRP1 Inflammasome.
Aoqi SongZhenghua WuWenjuan ZhaoWenqing ShiRu ChengJingjing JiangZhuojun NiHan QuXijier QiaolongbatuGuorong FanYuefen LouPublished in: Medicina (Kaunas, Lithuania) (2022)
Hyp is one of the main active components of HP, and Hyp has antidepressant effects through the NLRP1 inflammasome, which may be connected with the CXCL1/CXCR2/BDNF signaling pathway.
Keyphrases
- nlrp inflammasome
- signaling pathway
- major depressive disorder
- depressive symptoms
- pi k akt
- high fat diet induced
- epithelial mesenchymal transition
- stress induced
- induced apoptosis
- type diabetes
- metabolic syndrome
- cell migration
- bipolar disorder
- insulin resistance
- adipose tissue
- endoplasmic reticulum stress
- wild type