Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia.

Arun PradhanLixiao CheVladimir UstiyanAbid A RezaNicole M PekYufang ZhangAndrea B AlberTimothy R KalinJennifer A WambachMingxia GuDarrell N KottonMatthew E SiefertAssem G ZiadyTanya V KalinVladimir V Kalinichenko

Published in: American journal of respiratory and critical care medicine (2022)

TanFe is a novel activator of FOXF1, providing a new therapeutic candidate for treatment of ACDMPV and other neonatal pulmonary vascular diseases.

Keyphrases

pulmonary hypertension
endothelial cells
vascular endothelial growth factor
nuclear factor
combination therapy
immune response
inflammatory response