Atrial fibrillation (AF) stands as a prevalent and escalating cardiac arrhythmia in the United States, with obesity emerging as a prominent modifiable risk factor. This article explores the intricate relationship between obesity and AF, delving into the multifaceted pathophysiological mechanisms linking the 2 conditions. Various factors, such as autonomic dysfunction, left atrial stretch, inflammation, and hormonal imbalances, contribute to the initiation and perpetuation of AF in obese individuals. The Atrial Fibrillation Better Care pathway, emphasizing lifestyle modifications and weight loss strategies, emerges as a practical guideline for managing AF in obesity. This comprehensive review underscores the critical role of obesity as a significant modifiable risk factor for AF, urging a proactive approach to its management. Implementing the Atrial Fibrillation Better Care approach, focusing on encouraging physical activity, promoting healthy dietary habits, and raising awareness about the risks associated with obesity prove essential in preventing and mitigating the burden of AF in the obese population.
Keyphrases
- atrial fibrillation
- weight loss
- left atrial
- metabolic syndrome
- catheter ablation
- bariatric surgery
- insulin resistance
- oral anticoagulants
- roux en y gastric bypass
- left atrial appendage
- type diabetes
- direct oral anticoagulants
- weight gain
- gastric bypass
- heart failure
- high fat diet induced
- physical activity
- adipose tissue
- healthcare
- percutaneous coronary intervention
- oxidative stress
- glycemic control
- palliative care
- risk factors
- cardiovascular disease
- left ventricular
- body mass index
- depressive symptoms
- acute coronary syndrome
- human health
- mitral valve
- obese patients
- polycystic ovary syndrome
- venous thromboembolism
- coronary artery disease
- heart rate variability
- pain management