Development of a Sensitive Diagnostic Assay for Parkinson Disease Quantifying α-Synuclein-Containing Extracellular Vesicles.
Zhen HongChen TianTessandra StewartPatrick AroDavid SoltysMatt BercowLifu ShengKayla BordenTarek KhrisatCatherine PanCyrus P ZabetianElaine R PeskindJoseph F QuinnThomas J MontineJan AaslyMin ShiJing ZhangPublished in: Neurology (2021)
This study provides Class III evidence that total and aggregated α-syn-positive EVs in CSF identify patients with PD.