HIP1R and vimentin immunohistochemistry predict 1p/19q status in IDH-mutant glioma.

Marius FelixDennis FriedelAshok Kumar JayaveluKatharina FilipskiAnnekathrin ReinhardtUwe WarnkenDamian StichelDaniel SchrimpfAndrey KorshunovYueting WangTobias KesslerNima EtminanAndreas UnterbergChristel Herold-MendeLaura HeikausFelix Sahm Wolfgang WickPatrick N HarterAndreas von DeimlingDavid E Reuss

Published in: Neuro-oncology (2022)

We demonstrate that immunohistochemistry for HIP1R, vimentin, and ATRX predict 1p/19q status with 100% specificity and 95% sensitivity and therefore, constitutes a simple and inexpensive approach to the classification of IDH-mutant glioma.

Keyphrases

wild type
low grade
total hip arthroplasty
machine learning
deep learning
high grade