Distinct brain activity alterations of treatment for bipolar disorders with psychotherapy and drug therapy: activation likelihood estimation meta-analysis.
Jingyi LuoPengcheng YiMeng LiangShuyu ZhangQin TaoNi LiHan ZhangJialin WenXinrong XueChuan FanXiaoming LiPublished in: Psychological medicine (2023)
Our comprehensive meta-analysis indicates that these two treatments might have effect on BD in their own therapeutic modes. Psychotherapy might have a top-down effect, while drug therapy might have a bottom-up effect. This study may contribute to differential diagnosis of BDs and would be helpful to finding more accurate neuroimaging biomarkers for BD treatment.