Cerebral arteriolosclerosis, lacunar infarcts, and cognition in older Black adults.
Debra A FleischmanKonstantinos ArfanakisSue E LeurgansZoe ArvanitakisMelissa LamarS Duke HanVictoria N PooleDavid A BennettLisa L BarnesPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Older Black adults are at risk of cerebral small vessel disease (CSVD) and dementia. Examined magnetic resonance imaging-derived measure of arteriolosclerosis (ARTS), infarcts, and cognition. ARTS load was widely associated with lower cognition after adjusting for infarct load. Infarct load was specifically associated with lower complex attention. More within-Black in vivo studies of CSVD subtypes and cognition are needed.
Keyphrases
- mild cognitive impairment
- magnetic resonance imaging
- white matter
- subarachnoid hemorrhage
- physical activity
- acute myocardial infarction
- middle aged
- community dwelling
- working memory
- multiple sclerosis
- heart failure
- cognitive impairment
- cerebral ischemia
- magnetic resonance
- blood brain barrier
- acute coronary syndrome
- cerebral blood flow