Influence of ethylenediaminetetraacetic acid on regenerative endodontics: A systematic review.
Alexandre Henrique Dos Reis-PradoLucas Guimarães AbreuRogéria R FagundesSabrina de Castro OliveiraMarco Cicero BottinoAntônio Paulino Ribeiro SobrinhoFrancine BenettiPublished in: International endodontic journal (2022)
High-quality in vitro evidence suggests that EDTA-treated dentine positively influences TGF-β release, cell migration, attachment and differentiation; further research to evaluate its influence on tissue regeneration is necessary due to low methodological quality of the animal studies.