An amino acid transporter subunit as an antibody-drug conjugate target in colorectal cancer.

Juan Carlos MonteroSofía Del CarmenMar AbadJosé M SayaguésAntonio BarbáchanoAsunción Fernández-BarralAlberto MuñozAtanasio Pandiella

Published in: Journal of experimental & clinical cancer research : CR (2023)

The studies herewith reported indicate that CD98hc may represent a novel ADC target that, upon well-designed clinical trials, could be used to increase the therapeutic armamentarium against CRC.

Keyphrases

clinical trial
amino acid
cancer therapy
case control
magnetic resonance imaging
phase ii
diffusion weighted
diffusion weighted imaging
computed tomography
drug delivery
open label
nk cells
phase iii
study protocol