Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome.

Nadir YehyaBrian M VariscoNeal J ThomasHector R WongJason D ChristieRui Feng

Published in: Critical care (London, England) (2020)

We identified three sub-phenotypes of pediatric ARDS using whole blood transcriptomics. The sub-phenotypes had divergent clinical characteristics and prognoses. Further studies should validate these findings and investigate mechanisms underlying differences between sub-phenotypes.

Keyphrases

acute respiratory distress syndrome
extracorporeal membrane oxygenation
peripheral blood
mechanical ventilation
single cell
intensive care unit
case control