Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study.

Ming-Yi Zhao Jingyi Diao Peng Huang Jinqi Li Yihuan Li Yang Yang Liu Luo Senmao Zhang Letao Chen Tingting Wang Ping Zhu Jiabi Qin

Published in: Journal of diabetes research (2020)

These results suggest that maternal DM, NKX2.5 genetic variants, and their interactions are significantly associated with the risk of CHD in offspring.

Keyphrases

birth weight
pregnancy outcomes
young adults
glycemic control
high fat diet
genome wide
copy number
type diabetes
gestational age
pregnant women
weight gain
metabolic syndrome
adipose tissue
transcription factor
physical activity
body mass index
weight loss